October 2024: C. Levy: Breakthrough in cancer immunotherapy
Prof. Carmit Levy, Edmond J. Safra affiliate (Medicine), and colleagues have discovered a way to stimulate the immune system to fight cancer cells, even in types resistant to current immunotherapies.
Prof. Carmit Levy, Edmond J. Safra affiliate (Medicine), and colleagues have discovered a way to stimulate the immune system to fight cancer cells, even in types resistant to current immunotherapies.
Their breakthrough, published in Nature Communications, involves reversing a mechanism that prevents the immune system from attacking tumors. By studying how UV exposure suppresses the immune system, they found that UV radiation causes T cells to express high levels of the protein Ly6a, which acts as a brake on the immune system. By targeting Ly6a with antibodies, they were able to significantly reduce tumors in lab experiments, including those resistant to existing treatments.
The research team is now working to translate their findings into a drug for cancer patients, hoping to offer an effective new treatment.
The research had an extensive media coverage, including:
JERUSALEM POST, TIMES OF ISRAEL, ALLISRAEL, TERRASANTA,IFLSCIENCE, MEDTOUR, Sciencepost, TECHNOLOGY, ISRAELNOTICAS, Americanisraelite, MIRAGENEWS, JUDEAN.
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