Distinguished Speaker Series: A stochastic model of 3D Protein structure evolution
Prof. Jotun Hein, Chair of Bioinformatics, Department of Statistics, University of Oxford, UK.
Abstract:
In this talk I will discuss several computer science problems, inspired by my 15-years-long collaboration with Professor Eric Davidson, the foremost experimentalist of regulatory genomics, and rooted in his seminal research on causality, completeness, genomic Boolean logic, and genomically encoded regulatory information. Our collaboration produced the CYRENE cisGRN-Lexicon database containing the regulatory architecture of 600+ transcription-factor-encoding genes and other regulatory genes in eight species: human, mouse, fruit fly, sea urchin, nematode, rat, chicken, and zebrafish; and the CYRENE cisGRN-Browser, a full genome browser dedicated to cis-regulatory genomics.
For more details see here.
Sorin Istrail “Eric Davidson: Master of the Universe” Developmental Biology, Apr 15;412(s suppl) S47-54, 2016.
Host:
