A special seminar: Dr. Adi Goldenzweig, CTO Scala Biodesign: Computational protein design meets the industry
Dr. Adi Goldenzweig, CTO Scala Biodesign
A guest seminar: Computational Protein Design Meets the Industry
When & Where: Next Thursday, June 12th, 10am, Schreiber 006 (refreshments from 9:45).
Presenter: Dr. Adi Goldenzweig, CTO Scala Biodesign.
About Scala: Scala Biodesign offers computational protein design platforms to generate more potent proteins in a fraction of the time and effort. Scala’s solutions have proven effective for highly challenging proteins in diverse applications where conventional methods failed. Scala collaborates with top-tier pharmaceutical and chemical companies like Boehringer Ingelheim and Repsol. Scala was founded in 2022 by Dr. Ravit Netzer (CEO), Dr. Adi Glodenzweig (CTO), and Prof. Sarel Fleishman (Chief Scientist) based on a decade of research at the Weizmann Institute of Science.
Title: Computational Protein Design Meets the Industry
Abstract: Developing proteins as end products or for industrial processes requires multi-parameter optimization of their activity, stability, and manufacturability, which is currently laborious, iterative, and carries inherent tradeoffs. Scala Biodesign's computational protein design platforms combine atomistic design calculations, evolutionary analysis, and AI-based structure prediction to design more potent and stable proteins in one shot. Our technologies have been experimentally validated by over 50 research labs around the world as well as by pharmaceutical and chemical companies. These include a designed malaria vaccine candidate that has entered phase II clinical trials, as well as the generation of optimized enzymes for biocatalysis, dynamic protein targets and membrane proteins. In this lecture, I will present our platforms and highlight their successful use-cases, including our recent collaborations with Repsol and Boehringer Ingelheim, demonstrating their impact on industrial biocatalysis and drug development.
Hosts: Prof. Nir Ben-Tal and Dr. Jerome Tubiana.
The seminar is supported by the Edmond J. Safra Center for Bioinformatics.
