April 2022: Edmond J. Safra Biomedical Informatics Entrepreneurs Salon: "Computational design of smart antibodies"

Speaker:  Dr. Tzvika Hartman, SVP Computation, Biolojic Design



12 April 2022, 16:00 
Jaglom Auditorium, Tel Aviv University 
Edmond J. Safra Biomedical Informatics Entrepreneurs Salon

You are cordially invited to the Edmond J. Safra Biomedical Informatics Entrepreneurs Salon 


In collaboration with the Department of Biomedical Informatics at Harvard Medical School and the BIES series.


Speaker:  Dr. Tzvika Hartman, SVP Computation, Biolojic Design


Title: "Computational design of smart antibodies"


Tuesday, 12 April 2022, at 16:00



16:00-16:15 GATHERING
16:15-16:45 TALK
16:45-17:15 Q&A
17:15-18:00 RECEPTION


Abstract: Proteins are dynamic machines that can sense changes in the environment and respond to them. They can also activate other proteins or bind different targets under different conditions. However, currently, therapeutic proteins do not utilize the full potential of proteinst. Biolojic Design's computational platform designs dynamic antibodies that are programmed to respond to changes in the environment and to act differently under different biological conditions. This leads to better and safer therapies. The first such computationally designed antibody has been cleared for a phase 1/2 and will enter the clinic soon.
In this talk I'll start with a brief biological background and introduce some novel smart antibodies. I will continue with a description of Biolojic’s design process, which involves both computational and wet lab work. The major part of the talk will be dedicated to the computational aspects, which aim to compute and predict antibody properties based on both public and proprietary data.


The Salon is a bi-monthly forum to promote entrepreneurship at the convergence of biology, medicine, and computing.

In addition to hearing industry leaders speak, participants will have the chance to look for collaborators, employees, advisors, customers, or investors. Our goal is to generate a meeting, interaction and networking forum for academics, industry, entrepreneurs and venture capitalists interested in joining together biology, medicine and computing.


Organizing committee:

Prof. Noam Shomron, Chair

Prof. Ron Shamir

Guy Shapira

Gilit Zohar-Oren 


Contact: safrabio@tauex.tau.ac.il







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